I have a Bulldog puppy that was never able to get any milk from the mother. The vet said her chance of survival was 10%. So I took her in from the breeder and have nursed her from a bottle with Esbilac milk replacement powder. She is now 2 weeks old and doing GREAT, getting bigger and stronger everyday!!! No doubt now this babygirl is going to make it to a very happy home. I will always use this brand of milk replacer. It is a little more expensive than some of the other brands but it really is worth it. Know you are putting good quality nutrients into their precious little tummies.